منابع مشابه
Chemokines in renal diseases.
The interaction of activated leukocytes and renal resident cells is thought to play a crucial role in the pathogenesis of renal diseases. Recent investigations of the pathophysiological roles of chemokines and their cognate receptors have shed light on the detailed molecular mechanisms of leukocyte trafficking and activation in the diseased kidneys. Chemokine/chemokine receptor systems may be e...
متن کاملChemokines as Potential Markers in Pediatric Renal Diseases
Glomerular diseases and obstructive uropathies are the two most frequent causes of chronic kidney disease (CKD) in children. Recently, biomarkers have become a focus of clinical research as potentially useful diagnostic tools in pediatric renal diseases. Among several putative biomarkers, chemokines emerge as promising molecules since they play relevant roles in the pathophysiology of pediatric...
متن کاملChemokines in inflammatory bowel diseases.
Uncontrolled activation of mucosal effector cells has been identified as the main pathogenic mechanism involved in the initiation and perpetuation of mucosal inflammation in inflammatory bowel diseases (IBD). The sustained activation of these cells leads to the aberrant production of various pro-inflammatory mediators, which co-ordinated action amplifies the inflammatory process. In this settin...
متن کاملThe Relationship between Non-Renal Diseases and Renal Parenchymal Echogenicity in Children with Acute Abdominal Pain
Background Few results have shown that renal parenchymal echogenicity increases in pediatric patients with no concurrent renal diseases. This study aimed to investigate the relation between non-renal diseases and renal cortical echogenicity in children with acute abdominal pain. Materials and Methods This cross- sectional study was conducted among 100 children referred to Amirkola Children’s ...
متن کاملChemokines, chemokine receptors and renal disease.
gesting that, at least in this model, MCP-1 promoted Chemokines are proinflammatory cytokines that funcnearly exclusively tubular epithelial cell damage [5]. tion in leukocyte chemoattraction and activation. There Contrasting with the ample information about chemoare two major families of chemokines, termed CXC and kines and renal injury, so far, little is known about the CC, according to the p...
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ژورنال
عنوان ژورنال: The Scientific World JOURNAL
سال: 2005
ISSN: 1537-744X
DOI: 10.1100/tsw.2005.105